profile
Rafael Da-Silva-Custodio
Postdoctoral Researcher
Environment and Sustainability Institute
Environment and Sustainability Institute, University of Exeter, Penryn Campus, Penryn, Cornwall, TR10 9FE, UK
Overview
Qualifications
2009 MSc in Microbiology, University of Aveiro, Portugal
2008 Degree in Biology, University of Evora, Portugal
Career
2010-2012 Research Fellow, Institute for Molecular and Cell Biology, Porto, Portugal
Research
Research projects
Project Title: “Sphingosine-1-phosphate lyases as novel therapeutic targets in intracellular bacteria”
Supervisors: Dr Alan Brown and Dr Mitali Sarkar-Tyson
Funding Body: Defence Science and Technology Laboratory (Dstl)
Publications/Presentations:
Almeida MT, Mesquita FS, Cruz R, Osório H, Custódio R, Brito C, Vingadassalom D, Martins M, Leong JM, Holden DW, Cabanes D, Sousa S. (2015) Src-dependent Tyrosine Phosphorylation of Non-muscle Myosin Heavy Chain-IIA Restricts Listeria monocytogenes Cellular Infection. J Biol Chem. 2015 Jan 29. pii: jbc.M114.591313
Martins, M., Custodio, R., Camejo, A., Almeida, M.T., Cabanes, D. and Sousa, S. (2012) Listeria monocytogenes Triggers the Cell Surface Expression of Gp96 Protein and Interacts with Its N Terminus to Support Cellular Infection. THE JOURNAL OF BIOLOGICAL CHEMISTRY, VOL. 287, NO. 51, pp. 43083–43093